Liverpool vs Crystal Palace Prediction & Betting Tips (25 April) – Premier League

Liverpool welcome Crystal Palace to Anfield on Saturday with Champions League qualification now firmly within reach, but Arne Slot’s side still have work to do before anything is mathematically secure. The Reds arrive off the back of a dramatic Merseyside derby win, while Palace head to Merseyside with growing confidence of their own after extending their unbeaten Premier League run.
This is a game with contrasting priorities. Liverpool are pushing to lock down a top-five finish, whereas Crystal Palace have little left to chase in the league but are balancing domestic duties with a huge Conference League semi-final on the horizon. Even so, Oliver Glasner’s men have shown often enough in 2025 that they can still be awkward opponents for the Reds ⚽🔥
Match preview
Liverpool: Late derby drama keeps momentum alive
Liverpool’s victory over Everton last weekend could prove pivotal in their race for the Champions League. In another chaotic and emotional Merseyside derby, Virgil van Dijk popped up with a 100th-minute winner after Mohamed Salah and Beto had already traded goals, ensuring the Reds came away with bragging rights and three priceless points.
That late success also eased some of the pressure around Slot. Liverpool may still be set to surrender the title, but the broader picture is far from bleak. They sit fifth, five points clear of Brighton with a game in hand, and just a couple more positive results could be enough to secure Champions League football for next season.
Home form remains a major source of optimism. Liverpool have lost just one of their last 10 Premier League games at Anfield, and across their last five home matches in all competitions they have scored 15 goals. That firepower, coupled with the intensity of Anfield late in the season, makes them formidable.
The task now is to finish the job. Slot’s side cannot afford complacency against a Palace team that has enjoyed recent success in this fixture and comes into the weekend on a respectable run of its own.
Crystal Palace: Steady, stubborn and with Europe on the mind
Crystal Palace may not have much left to fight for in the Premier League, but that does not mean the Eagles are drifting. Monday’s goalless draw with West Ham extended their unbeaten league run, and more broadly they have turned their form around impressively after a dreadful winter spell.
Following a 12-match winless sequence between mid-December and early February, Glasner’s side have won seven of their last 14 matches in all competitions. They also head to Anfield unbeaten in four Premier League games since a narrow defeat to Manchester United in March.
The biggest challenge for Palace is managing priorities. A Conference League semi-final first leg against Shakhtar Donetsk awaits in Poland just five days after this match, so some attention will naturally be drifting toward Europe. Glasner rotated for the draw with West Ham, and with that continental tie looming, squad management is inevitable.
Still, Palace have shown they can juggle both fronts. They also have recent evidence that Liverpool are a team they can trouble. Across the Premier League, EFL Cup and Community Shield in 2025, Palace took three wins and a draw from four meetings with the Reds. That kind of recent record should ensure they arrive without fear.
Form guide 📊
Liverpool Premier League form:
Strong recent home form, boosted by a dramatic derby win
Liverpool form (all competitions):
Only one defeat in their last 10 top-flight home games
Crystal Palace Premier League form:
Unbeaten in four since the defeat to Manchester United
Crystal Palace form (all competitions):
Seven wins from the last 14 after a difficult winter run
Liverpool clearly have the stronger motivation in league terms, but Palace are organised, improving and comfortable in this matchup. The hosts should have more urgency, though the visitors are capable of making this awkward.
Team news & predicted lineups 🧤
Liverpool
Liverpool have a goalkeeping issue to manage after Giorgi Mamardashvili suffered a knee wound against Everton that required hospital treatment. With Alisson Becker also still unavailable, Freddie Woodman is set for a full Premier League debut for the Reds.
Wataru Endo, Hugo Ekitike, Conor Bradley and Giovanni Leoni remain out, while Joe Gomez is also a doubt with a muscular problem. Slot may otherwise keep faith with the attacking core that helped them through the derby.
Liverpool possible starting lineup:
Woodman; Jones, Konate, Van Dijk, Kerkez; Gravenberch, Szoboszlai; Salah, Wirtz, Gakpo; Isak
Crystal Palace
Palace are monitoring Adam Wharton after the midfielder missed the draw with West Ham due to an adductor issue, the same problem that forced him out of the England camp in March. Maxence Lacroix recovered from his Fiorentina knock to feature on Monday, so he should be fine here.
Cheick Doucoure, Evann Guessand and Eddie Nketiah are all definitely unavailable. After rotating against West Ham, Glasner is expected to restore several regulars, including Jean-Philippe Mateta and the in-form Ismaila Sarr, who has scored in each of his last four matches against Liverpool.
Crystal Palace possible starting lineup:
Henderson; Canvot, Richards, Lacroix; Munoz, Hughes, Kamada, Mitchell; Sarr, Johnson; Mateta
Key stats & betting angles 🔍
- Liverpool are fifth and five points clear of Brighton with a game in hand.
- Virgil van Dijk scored a 100th-minute winner in the Merseyside derby last weekend.
- The Reds have lost only one of their last 10 Premier League home games.
- Liverpool have scored 15 goals in their last five home matches in all competitions.
- Crystal Palace are unbeaten in four Premier League matches.
- The Eagles have won seven of their last 14 games in all competitions.
- Palace took three wins and a draw from four meetings with Liverpool in 2025.
- Ismaila Sarr has scored in each of his last four appearances against Liverpool.
Prediction ⚽
Crystal Palace have been awkward opponents for Liverpool recently, and with Sarr, Mateta and a well-drilled back line, the visitors should create a few problems. However, this game means more to Liverpool in league terms, and the Reds’ home form suggests they usually find a way at Anfield.
Palace’s looming Conference League semi-final may also affect intensity late on, especially if Glasner has one eye on protecting key players. Expect a competitive game, but Liverpool’s greater urgency and firepower should prove decisive.
Likely result: Liverpool win
Best betting angle: Liverpool win & Both Teams to Score
Correct score prediction: Liverpool 2–1 Crystal Palace
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